5EFH

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trifluoroketone transition state analogue

Summary for 5EFH

Entry DOI	10.2210/pdb5efh/pdb
Related	5EDU 5EEF 5EEI 5EEK 5EEM 5EEN 5EF7 5EF8 5EFB 5EFG 5EFJ 5EFK 5EFN
Descriptor	Hdac6 protein, ZINC ION, POTASSIUM ION, ... (8 entities in total)
Functional Keywords	hydrolase
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	2
Total formula weight	82088.23
Authors	Hai, Y.,Christianson, D.W. (deposition date: 2015-10-23, release date: 2016-07-27, Last modification date: 2023-09-27)
Primary citation	Hai, Y.,Christianson, D.W. Histone deacetylase 6 structure and molecular basis of catalysis and inhibition. Nat.Chem.Biol., 12:741-747, 2016 Cited by PubMed: 27454933 DOI: 10.1038/nchembio.2134 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.162 Å)

Structure validation