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5TD7
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BU of 5td7 by Molmil
Crystal structure of histone deacetylase 10
Descriptor: 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ...
Authors:Hai, Y, Shinsky, S.A, Porter, N.J, Christianson, D.W.
Deposit date:2016-09-17
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Histone deacetylase 10 structure and molecular function as a polyamine deacetylase.
Nat Commun, 8, 2017
5HJ9
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BU of 5hj9 by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE
Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HJA
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BU of 5hja by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP
Descriptor: (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4MYF
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BU of 4myf by Molmil
Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0
Descriptor: Formiminoglutamase, MANGANESE (II) ION
Authors:Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
Deposit date:2013-09-27
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYK
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BU of 4myk by Molmil
Crystal structure of Trypanosoma cruzi formiminoglutamase (oxidized) with Mn2+2 at pH 8.5
Descriptor: Formiminoglutamase, MANGANESE (II) ION
Authors:Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
Deposit date:2013-09-27
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MXR
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BU of 4mxr by Molmil
Crystal structure of Trypanosoma cruzi formiminoglutamase with Mn2+2
Descriptor: Formiminoglutamase, GLYCEROL, MANGANESE (II) ION
Authors:Hai, Y, Dugery, R.-J, Healy, D, Christianson, D.W.
Deposit date:2013-09-26
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYN
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BU of 4myn by Molmil
Crystal structure of Trypanosoma cruzi formiminoglutamase N114H variant with Mn2+2
Descriptor: Formiminoglutamase, MANGANESE (II) ION
Authors:Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
Deposit date:2013-09-27
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYL
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BU of 4myl by Molmil
Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6
Descriptor: Formiminoglutamase
Authors:Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
Deposit date:2013-09-27
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.531 Å)
Cite:Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
5EFB
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BU of 5efb by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with oxamflatin
Descriptor: Hdac6 protein, Oxamflatin, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.543 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EF7
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BU of 5ef7 by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HPOB
Descriptor: 4-[2-[2-hydroxyethyl(phenyl)amino]-2-oxidanylidene-ethyl]-~{N}-oxidanyl-benzamide, Hdac6 protein, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EFN
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BU of 5efn by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (H574A) in complex with histone H4 Lys6 tripeptide substrate
Descriptor: 1,2-ETHANEDIOL, 7-AMINO-4-METHYL-CHROMEN-2-ONE, Hdac6 protein, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-24
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEI
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BU of 5eei by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-22
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EFG
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BU of 5efg by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with acetate
Descriptor: ACETATE ION, Hdac6 protein, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEK
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BU of 5eek by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEF
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BU of 5eef by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 in complex with trichostatin A
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, HDAC6, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-22
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEN
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BU of 5een by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat
Descriptor: Belinostat, CHLORIDE ION, Hdac6 protein, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EFK
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BU of 5efk by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (Y745F mutant) in complex with alpha tubulin K40 tripeptide substrate
Descriptor: 1,2-ETHANEDIOL, 7-AMINO-4-METHYL-CHROMEN-2-ONE, DI(HYDROXYETHYL)ETHER, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EFH
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BU of 5efh by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trifluoroketone transition state analogue
Descriptor: 1,2-ETHANEDIOL, 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol, BROMIDE ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EDU
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BU of 5edu by Molmil
Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Descriptor: Maltose-binding periplasmic protein, Histone deacetylase 6 chimera, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-22
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EF8
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BU of 5ef8 by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Hdac6 protein, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EFJ
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BU of 5efj by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, HC toxin, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEM
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BU of 5eem by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2
Descriptor: FORMIC ACID, Hdac6 protein, POTASSIUM ION, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2015-10-23
Release date:2016-07-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
4Q3V
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BU of 4q3v by Molmil
Crystal structure of Schistosoma mansoni arginase in complex with inhibitor BEC
Descriptor: Arginase, GLYCEROL, MANGANESE (II) ION, ...
Authors:Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W.
Deposit date:2014-04-12
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
Biochemistry, 53, 2014
4Q3P
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BU of 4q3p by Molmil
Crystal structure of Schistosoma mansoni arginase
Descriptor: Arginase, GLYCEROL, MANGANESE (II) ION
Authors:Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W.
Deposit date:2014-04-12
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
Biochemistry, 53, 2014
4Q41
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BU of 4q41 by Molmil
Crystal structure of Schistosoma mansoni arginase in complex with L-lysine
Descriptor: Arginase, GLYCEROL, LYSINE, ...
Authors:Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W.
Deposit date:2014-04-12
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
Biochemistry, 53, 2014

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