5EDU
Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Summary for 5EDU
| Entry DOI | 10.2210/pdb5edu/pdb |
| Related | 5EEF 5EEI 5EEK 5EEM 5EEN 5EF7 5EF8 5EFB 5EFG 5EFH 5EFJ 5EFK 5EFN |
| Related PRD ID | PRD_900001 |
| Descriptor | Maltose-binding periplasmic protein, Histone deacetylase 6 chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, TRICHOSTATIN A, ... (6 entities in total) |
| Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 2 |
| Total formula weight | 164615.24 |
| Authors | Hai, Y.,Christianson, D.W. (deposition date: 2015-10-22, release date: 2016-07-27, Last modification date: 2023-09-27) |
| Primary citation | Hai, Y.,Christianson, D.W. Histone deacetylase 6 structure and molecular basis of catalysis and inhibition. Nat.Chem.Biol., 12:741-747, 2016 Cited by PubMed: 27454933DOI: 10.1038/nchembio.2134 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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