4ZU7

X-ray structure if the QdtA 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, double mutant Y17R/R97H, in complex with TDP

Summary for 4ZU7

Entry DOI	10.2210/pdb4zu7/pdb
Descriptor	QdtA, THYMIDINE-5'-DIPHOSPHATE, (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, ... (4 entities in total)
Functional Keywords	cupin isomerase 3-4-ketoisomerase, isomerase
Biological source	Thermoanaerobacterium thermosaccharolyticum
Total number of polymer chains	8
Total formula weight	140712.31
Authors	Thoden, J.B.,Vinogradov, E.,Gilbert, M.,Salinger, A.J.,Holden, H.M. (deposition date: 2015-05-15, release date: 2015-07-15, Last modification date: 2023-09-27)
Primary citation	Thoden, J.B.,Vinogradov, E.,Gilbert, M.,Salinger, A.J.,Holden, H.M. Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry. Biochemistry, 54:4495-4506, 2015 Cited by PubMed: 26125548 DOI: 10.1021/acs.biochem.5b00541 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation