4Y2P
Structure of soluble epoxide hydrolase in complex with N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine
Summary for 4Y2P
Entry DOI | 10.2210/pdb4y2p/pdb |
Related | 4Y2J 4Y2Q 4Y2R 4Y2S 4Y2T 4Y2U 4Y2V 4Y2X 4Y2Y |
Descriptor | Bifunctional epoxide hydrolase 2, MAGNESIUM ION, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine, ... (4 entities in total) |
Functional Keywords | inhibitor complex, hydrolase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 63737.08 |
Authors | Amano, Y.,Yamaguchi, T. (deposition date: 2015-02-10, release date: 2015-05-06, Last modification date: 2024-03-20) |
Primary citation | Amano, Y.,Tanabe, E.,Yamaguchi, T. Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening Bioorg.Med.Chem., 23:2310-2317, 2015 Cited by PubMed: 25862210DOI: 10.1016/j.bmc.2015.03.083 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report