4U7C

Structure of DNA polymerase kappa in complex with benzopyrene adducted DNA

Summary for 4U7C

• Entry DOI: 10.2210/pdb4u7c/pdb
• Related: 4U6P
• Descriptor: DNA polymerase kappa, DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*P*AP*TP*GP*(VKJ)P*CP*TP*GP*AP*TP*CP*CP*GP*C)-3'), ... (8 entities in total)
• Functional Keywords: benzo[a]pyrene-n2-guanine, dna replication, dna damage tolerance, polymerase kappa, environment pollution, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 127741.36

Authors

Jha, V.K.,Ling, H. (deposition date: 2014-07-30, release date: 2016-01-27, Last modification date: 2023-09-27)

• Primary citation: Jha, V.,Bian, C.,Xing, G.,Ling, H.; Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa.; Nucleic Acids Res., 44:4957-4967, 2016; PubMed: 27034468; DOI: 10.1093/nar/gkw204

Experimental method

X-RAY DIFFRACTION (2.8 Å)