4TYA

An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline

Summary for 4TYA

Entry DOI	10.2210/pdb4tya/pdb
Related	4TXF 4TXS 4TY8 4TY9 4TYB
Descriptor	Polyprotein, 4-(trifluoromethyl)benzoic acid (2 entities in total)
Functional Keywords	inhibitor, ns5b, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Hepatitis C virus
Total number of polymer chains	4
Total formula weight	251928.41
Authors	Shui, W.,Yang, C.,Lin, J.,Chen, X.,Qin, S.,Chen, S. (deposition date: 2014-07-08, release date: 2015-05-06, Last modification date: 2024-03-20)
Primary citation	Chen, X.,Qin, S.,Chen, S.,Li, J.,Li, L.,Wang, Z.,Wang, Q.,Lin, J.,Yang, C.,Shui, W. A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5:8361-8361, 2015 Cited by PubMed: 25666181 DOI: 10.1038/srep08361 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.94 Å)

Structure validation