4ROF
Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide
Summary for 4ROF
Entry DOI | 10.2210/pdb4rof/pdb |
Related | 4ROH 4ROI 4ROJ |
Descriptor | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein (3 entities in total) |
Functional Keywords | structural genomics, structural genomicsconsortium, sgc, ligase, structural genomics consortium |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : Q96J02 Cytoplasm : Q9H3M7 |
Total number of polymer chains | 4 |
Total formula weight | 13543.10 |
Authors | Liu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2014-10-28, release date: 2014-12-10, Last modification date: 2023-09-20) |
Primary citation | Liu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide To be Published, |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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