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4ROJ

Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide

Summary for 4ROJ
Entry DOI10.2210/pdb4roj/pdb
Related4ROF 4ROH 4ROI
DescriptorGuanine nucleotide exchange factor VAV2, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywordsstructural genomics, sh2 domain, structural genomics consortium, sgc, ligase
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm : Q9H3M7
Total number of polymer chains6
Total formula weight45594.02
Authors
Liu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2014-10-28, release date: 2014-12-10, Last modification date: 2023-12-06)
Primary citationLiu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC)
Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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