4RJT

Crystal Structure of Unliganded, Full Length hUGDH at pH 7.0

Summary for 4RJT

• Entry DOI: 10.2210/pdb4rjt/pdb
• Related: 2Q3E 2QG4 3PRJ 3PTZ 3TF5 4QEJ
• Descriptor: UDP-glucose 6-dehydrogenase, CHLORIDE ION (3 entities in total)
• Functional Keywords: oxidoreductase, rossman fold, nucleotide sugar dehydrogenase, nad binding, udp-glucose binding, oxidation, cytosol
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 165423.63

Authors

Sidlo, A.M.,Wood, Z.A. (deposition date: 2014-10-09, release date: 2014-12-31, Last modification date: 2023-09-20)

• Primary citation: Kadirvelraj, R.,Custer, G.S.,Keul, N.D.,Sennett, N.C.,Sidlo, A.M.,Walsh Jr., R.M.,Wood, Z.A.; Hysteresis in Human UDP-Glucose Dehydrogenase Is Due to a Restrained Hexameric Structure That Favors Feedback Inhibition.; Biochemistry, 53:8043-8051, 2014; PubMed: 25478983; DOI: 10.1021/bi500594x

Experimental method

X-RAY DIFFRACTION (2.7 Å)