2Q3E
Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
Summary for 2Q3E
Entry DOI | 10.2210/pdb2q3e/pdb |
Descriptor | UDP-glucose 6-dehydrogenase, CHLORIDE ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | udp-glucose 6-dehydrogenase, hexamer, structural genomics, structural genomics consortium, sgc, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 640207.37 |
Authors | Kavanagh, K.L.,Guo, K.,Bunkoczi, G.,Savitsky, P.,Pilka, E.,Bhatia, C.,Smee, C.,Berridge, G.,von Delft, F.,Wiegelt, J.,Arrowsmith, C.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-05-30, release date: 2007-07-03, Last modification date: 2023-08-30) |
Primary citation | Egger, S.,Chaikuad, A.,Kavanagh, K.L.,Oppermann, U.,Nidetzky, B. Structure and mechanism of human UDP-glucose 6-dehydrogenase. J.Biol.Chem., 286:23877-23887, 2011 Cited by PubMed: 21502315DOI: 10.1074/jbc.M111.234682 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report