4PVL
X-ray structure of human transthyretin (TTR) at room temperature to 1.9A resolution
Summary for 4PVL
Entry DOI | 10.2210/pdb4pvl/pdb |
Related | 2PAB 3IPE 3U2I 4PVM 4PVN |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | beta sandwich, transport protein, serum |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28073.38 |
Authors | Fisher, S.J.,Blakeley, M.P.,Haupt, M.,Mason, S.A.,Cooper, J.B.,Mitchell, E.P.,Forsyth, V.T. (deposition date: 2014-03-18, release date: 2014-11-12, Last modification date: 2023-11-08) |
Primary citation | Haupt, M.,Blakeley, M.P.,Fisher, S.J.,Mason, S.A.,Cooper, J.B.,Mitchell, E.P.,Forsyth, V.T. Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1:429-438, 2014 Cited by PubMed: 25485123DOI: 10.1107/S2052252514021113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.851 Å) |
Structure validation
Download full validation report