4PPR

Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem

Summary for 4PPR

Entry DOI	10.2210/pdb4ppr/pdb
Related	4P0M
Descriptor	Penicillin-binding protein DacB1, (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid (3 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, tb structural genomics consortium, tbsgc, penicillin-binding protein, peptidoglycan d, d-peptidase, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	35100.28
Authors	Prigozhin, D.M.,Huizar, J.P.,Mavrici, D.,Alber, T.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2014-02-27, release date: 2014-11-05, Last modification date: 2023-09-20)
Primary citation	Prigozhin, D.M.,Krieger, I.V.,Huizar, J.P.,Mavrici, D.,Waldo, G.S.,Hung, L.W.,Sacchettini, J.C.,Terwilliger, T.C.,Alber, T. Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. Plos One, 9:e116249-e116249, 2014 Cited by PubMed: 25551456 DOI: 10.1371/journal.pone.0116249 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation