4P0M

Crystal structure of an evolved putative penicillin-binding protein homolog, Rv2911, from Mycobacterium tuberculosis

Replaces:  2BCF

Summary for 4P0M

• Entry DOI: 10.2210/pdb4p0m/pdb
• Descriptor: D-alanyl-D-alanine carboxypeptidase (2 entities in total)
• Functional Keywords: penicillin-binding protein, dd-2 carboxypeptidase, directed evolution, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, hydrolase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 29072.50

Authors

Krieger, I.,Yu, M.,Bursey, E.,Hung, L.-W.,Terwilliger, T.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2014-02-21, release date: 2014-03-12, Last modification date: 2023-12-27)

• Primary citation: Prigozhin, D.M.,Krieger, I.V.,Huizar, J.P.,Mavrici, D.,Waldo, G.S.,Hung, L.,Sacchettini, J.C.,Terwilliger, T.C.,Alber, T.; Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis.; Plos One, 9:e116249-e116249, 2014; PubMed: 25551456; DOI: 10.1371/journal.pone.0116249

Experimental method

X-RAY DIFFRACTION (2 Å)