4PP6
Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Resveratrol
Summary for 4PP6
Entry DOI | 10.2210/pdb4pp6/pdb |
Related | 4PPP 4PPS |
Descriptor | Estrogen receptor, Nuclear receptor coactivator 2, RESVERATROL, ... (4 entities in total) |
Functional Keywords | nuclear hormone receptor, transcription factor, ligand binding, nucleus, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform 1: Nucleus. Isoform 3: Nucleus. Nucleus: P03372 Nucleus: Q15596 |
Total number of polymer chains | 4 |
Total formula weight | 58398.82 |
Authors | Nwachukwu, J.C.,Srinivasan, S.,Bruno, N.E.,Parent, A.A.,Hughes, T.S.,Pollock, J.A.,Gjyshi, O.,Cavett, V.,Nowak, J.,Garcia-Ordonez, R.D.,Houtman, R.,Griffin, P.R.,Kojetin, D.J.,Katzenellenbogen, J.A.,Conkright, M.D.,Nettles, K.W. (deposition date: 2014-02-26, release date: 2014-05-07, Last modification date: 2023-09-20) |
Primary citation | Nwachukwu, J.C.,Srinivasan, S.,Bruno, N.E.,Parent, A.A.,Hughes, T.S.,Pollock, J.A.,Gjyshi, O.,Cavett, V.,Nowak, J.,Garcia-Ordonez, R.D.,Houtman, R.,Griffin, P.R.,Kojetin, D.J.,Katzenellenbogen, J.A.,Conkright, M.D.,Nettles, K.W. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife, 3:e02057-e02057, 2014 Cited by PubMed: 24771768DOI: 10.7554/eLife.02057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.201 Å) |
Structure validation
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