4PLK

Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12

Summary for 4PLK

• Entry DOI: 10.2210/pdb4plk/pdb
• Related: 4PLJ
• Descriptor: Capsid protein, 8G12 light chain, 8G12 heavy chain (3 entities in total)
• Functional Keywords: complex, neutralizing antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Hepatitis E virus (HEV); More
• Total number of polymer chains: 12
• Total formula weight: 255248.02

Authors

Tang, X.H.,Li, S.W.,Sivaraman, J. (deposition date: 2014-05-18, release date: 2015-04-08, Last modification date: 2015-05-13)

• Primary citation: Gu, Y.,Tang, X.,Zhang, X.,Song, C.,Zheng, M.,Wang, K.,Zhang, J.,Ng, M.H.,Hew, C.L.,Li, S.,Xia, N.,Sivaraman, J.; Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody; Cell Res., 25:604-620, 2015; PubMed: 25793314; DOI: 10.1038/cr.2015.34

Experimental method

X-RAY DIFFRACTION (4 Å)