4OYW

Crystal Structure of Human Soluble Adenylate Cyclase

Summary for 4OYW

• Entry DOI: 10.2210/pdb4oyw/pdb
• Related: 4OYA 4OYB 4OYI 4OYM 4OYO 4OYP 4OYX 4OYZ 4OZ2 4OZ3
• Descriptor: Adenylate cyclase type 10, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: adenylate cyclase, lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q96PN6
• Total number of polymer chains: 1
• Total formula weight: 53594.38

Authors

Vinkovic, M. (deposition date: 2014-02-13, release date: 2014-04-02, Last modification date: 2023-12-27)

• Primary citation: Saalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H.; Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.; Chemmedchem, 9:823-832, 2014; PubMed: 24616449; DOI: 10.1002/cmdc.201300480

Experimental method

X-RAY DIFFRACTION (1.7 Å)