4OYA

Human solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone

Summary for 4OYA

• Entry DOI: 10.2210/pdb4oya/pdb
• Related: 4OYB 4OYI 4OYM 4OYO 4OYP 4OYW 4OYX 4OYZ 4OZ2 4OZ3
• Descriptor: Adenylate cyclase type 10, (4-azanyl-1,2,5-oxadiazol-3-yl)-[3-(1H-benzimidazol-2-ylmethoxy)phenyl]methanone, GLYCEROL, ... (4 entities in total)
• Functional Keywords: lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : Q96PN6
• Total number of polymer chains: 1
• Total formula weight: 53894.24

Authors

Vinkovic, M. (deposition date: 2014-02-11, release date: 2014-04-02, Last modification date: 2023-12-27)

• Primary citation: Saalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H.; Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.; Chemmedchem, 9:823-832, 2014; PubMed: 24616449; DOI: 10.1002/cmdc.201300480

Experimental method

X-RAY DIFFRACTION (2.03 Å)