4OJ4

Crystal structure of V290M PPARgamma mutant in complex with diclofenac

Summary for 4OJ4

• Entry DOI: 10.2210/pdb4oj4/pdb
• Related: 1PRG 3SZ1
• Descriptor: Peroxisome proliferator-activated receptor gamma, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: mainly alpha helix, nuclear receptor, transcription factor, rxr, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 32143.24

Authors

Puhl, A.C.,Webb, P.,Polikarpov, I. (deposition date: 2014-01-20, release date: 2015-02-04, Last modification date: 2024-02-28)

• Primary citation: Puhl, A.C.,Bernardes, A.,Polikarpov, I.,Webb, P.; Crystal structure of a PPAR ligand-resistance syndrome mutant; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)