1PRG
LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Summary for 1PRG
Entry DOI | 10.2210/pdb1prg/pdb |
Descriptor | PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA) (2 entities in total) |
Functional Keywords | thiazolidinedione, ligand-binding domain, nuclear receptor, apo, transcription factor, orphan receptor, gene regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 61667.70 |
Authors | Nolte, R.T.,Wisely, G.B.,Milburn, M.V. (deposition date: 1998-07-02, release date: 2001-01-13, Last modification date: 2023-12-27) |
Primary citation | Nolte, R.T.,Wisely, G.B.,Westin, S.,Cobb, J.E.,Lambert, M.H.,Kurokawa, R.,Rosenfeld, M.G.,Willson, T.M.,Glass, C.K.,Milburn, M.V. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature, 395:137-143, 1998 Cited by PubMed: 9744270DOI: 10.1038/25931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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