4OCS
Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody
Summary for 4OCS
Entry DOI | 10.2210/pdb4ocs/pdb |
Related | 4OCR 4OCW 4OD1 4OD3 4ODH 4ORG |
Descriptor | CAP256-VRC26.10 light chain, CAP256-VRC26.10 heavy chain (3 entities in total) |
Functional Keywords | fab, hiv-1, v1v2, cap256, vrc26, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 50942.92 |
Authors | Gorman, J.,Doria-Rose, N.A.,Schramm, C.A.,Moore, P.L.,Mascola, J.R.,Shapiro, L.,Morris, L.,Kwong, P.D. (deposition date: 2014-01-09, release date: 2014-02-26, Last modification date: 2023-12-06) |
Primary citation | Doria-Rose, N.A.,Schramm, C.A.,Gorman, J.,Moore, P.L.,Bhiman, J.N.,Dekosky, B.J.,Ernandes, M.J.,Georgiev, I.S.,Kim, H.J.,Pancera, M.,Staupe, R.P.,Altae-Tran, H.R.,Bailer, R.T.,Crooks, E.T.,Cupo, A.,Druz, A.,Garrett, N.J.,Hoi, K.H.,Kong, R.,Louder, M.K.,Longo, N.S.,McKee, K.,Nonyane, M.,O'Dell, S.,Roark, R.S.,Rudicell, R.S.,Schmidt, S.D.,Sheward, D.J.,Soto, C.,Wibmer, C.K.,Yang, Y.,Zhang, Z.,Sequencing, Nisc Comparative,Mullikin, J.C.,Binley, J.M.,Sanders, R.W.,Wilson, I.A.,Moore, J.P.,Ward, A.B.,Georgiou, G.,Williamson, C.,Abdool Karim, S.S.,Morris, L.,Kwong, P.D.,Shapiro, L.,Mascola, J.R. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509:55-62, 2014 Cited by PubMed: 24590074DOI: 10.1038/nature13036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.901 Å) |
Structure validation
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