4NUV
Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Summary for 4NUV
Entry DOI | 10.2210/pdb4nuv/pdb |
Related | 4NUU |
Descriptor | Duffy receptor, Duffy antigen/chemokine receptor, GLYCEROL, ... (4 entities in total) |
Functional Keywords | duffy binding like (dbl) domain fold, gpcr, adhesion, invasion, red blood cell binding, chemokine binding, duffy antigen receptor for chemokines, membrane, membrane protein, protein binding, cell invasion |
Biological source | Plasmodium vivax More |
Cellular location | Membrane; Single-pass type I membrane protein: P22290 Early endosome: Q16570 |
Total number of polymer chains | 4 |
Total formula weight | 82661.50 |
Authors | Tolia, N.H. (deposition date: 2013-12-04, release date: 2014-02-05, Last modification date: 2024-03-13) |
Primary citation | Batchelor, J.D.,Malpede, B.M.,Omattage, N.S.,Dekoster, G.T.,Henzler-Wildman, K.A.,Tolia, N.H. Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC. Plos Pathog., 10:e1003869-e1003869, 2014 Cited by PubMed: 24415938DOI: 10.1371/journal.ppat.1003869 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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