4NUU

Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)

Summary for 4NUU

Entry DOI	10.2210/pdb4nuu/pdb
Related	4NUV
Descriptor	Duffy receptor, Duffy antigen/chemokine receptor (3 entities in total)
Functional Keywords	duffy binding like (dbl) domain fold, gpcr, adhesion, invasion, red blood cell binding, chemokine binding, duffy antigen receptor for chemokines, membrane, membrane protein, protein binding, cell invasion
Biological source	Plasmodium vivax More
Cellular location	Membrane; Single-pass type I membrane protein: P22290 Early endosome: Q16570
Total number of polymer chains	3
Total formula weight	78618.49
Authors	Tolia, N.H. (deposition date: 2013-12-04, release date: 2014-02-05, Last modification date: 2024-03-13)
Primary citation	Batchelor, J.D.,Malpede, B.M.,Omattage, N.S.,Dekoster, G.T.,Henzler-Wildman, K.A.,Tolia, N.H. Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC. Plos Pathog., 10:e1003869-e1003869, 2014 Cited by PubMed: 24415938 DOI: 10.1371/journal.ppat.1003869 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation