4NUJ

Crystal structure of HIV-1 broadly neutralizing antibody PGT152

Summary for 4NUJ

• Entry DOI: 10.2210/pdb4nuj/pdb
• Descriptor: PGT152 light chain, PGT152 heavy chain (3 entities in total)
• Functional Keywords: immunoglobulin, fab fragment, immune system, hiv envelope
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 50078.11

Authors

Blattner, C.,Wilson, I.A. (deposition date: 2013-12-03, release date: 2014-05-14, Last modification date: 2023-09-20)

• Primary citation: Blattner, C.,Lee, J.H.,Sliepen, K.,Derking, R.,Falkowska, E.,de la Pena, A.T.,Cupo, A.,Julien, J.P.,van Gils, M.,Lee, P.S.,Peng, W.,Paulson, J.C.,Poignard, P.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Wilson, I.A.,Ward, A.B.; Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.; Immunity, 40:669-680, 2014; PubMed: 24768348; DOI: 10.1016/j.immuni.2014.04.008

Experimental method

X-RAY DIFFRACTION (1.827 Å)