4NKH

Crystal structure of SspH1 LRR domain

Summary for 4NKH

• Entry DOI: 10.2210/pdb4nkh/pdb
• Related: 4NKG
• Descriptor: E3 ubiquitin-protein ligase sspH1 (1 entity in total)
• Functional Keywords: leucine-rich repeat, e3 ligase substrate interaction domain, ligase
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium
• Cellular location: Secreted: D0ZVG2
• Total number of polymer chains: 6
• Total formula weight: 154693.01

Authors

Keszei, A.F.A.,Xiaojing, T.,Mccormick, C.,Zeqiraj, E.,Rohde, J.R.,Tyers, M.,Sicheri, F. (deposition date: 2013-11-12, release date: 2013-12-11, Last modification date: 2024-02-28)

• Primary citation: Keszei, A.F.,Tang, X.,McCormick, C.,Zeqiraj, E.,Rohde, J.R.,Tyers, M.,Sicheri, F.; Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase.; Mol.Cell.Biol., 34:362-373, 2014; PubMed: 24248594; DOI: 10.1128/MCB.01360-13

Experimental method

X-RAY DIFFRACTION (2.75 Å)