4NKG

Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain

Summary for 4NKG

Entry DOI	10.2210/pdb4nkg/pdb
Related	4NKH
Descriptor	E3 ubiquitin-protein ligase sspH1, Serine/threonine-protein kinase N1, HEXANE-1,6-DIOL, ... (4 entities in total)
Functional Keywords	leucine-rich repeat, coiled-coil, e3 ligase substrate interaction, ligase-transferase complex, ligase/transferase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium More
Cellular location	Secreted: D0ZVG2 Cytoplasm: Q16512
Total number of polymer chains	4
Total formula weight	71529.43
Authors	Keszei, A.F.A.,Xiaojing, T.,Mccormick, C.,Zeqiraj, E.,Rohde, J.R.,Tyers, M.,Sicheri, F. (deposition date: 2013-11-12, release date: 2013-12-11, Last modification date: 2024-02-28)
Primary citation	Keszei, A.F.,Tang, X.,McCormick, C.,Zeqiraj, E.,Rohde, J.R.,Tyers, M.,Sicheri, F. Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Mol.Cell.Biol., 34:362-373, 2014 Cited by PubMed: 24248594 DOI: 10.1128/MCB.01360-13 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation