4MV5

IspH in complex with 6-chloropyridin-3-ylmethyl diphosphate

Summary for 4MV5

Entry DOI	10.2210/pdb4mv5/pdb
Related	3DNF 3F7T 3KE8 4MUX 4MUY 4MV0
Descriptor	4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, (6-chloropyridin-3-yl)methyl trihydrogen diphosphate, ... (4 entities in total)
Functional Keywords	iron-sulfur protein, reductase, 6-chloropyridin-3-ylmethyl diphosphate, cytosol, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	73414.53
Authors	Span, I.,Wang, K.,Song, Y.,Eisenreich, W.,Bacher, A.,Oldfield, E.,Groll, M. (deposition date: 2013-09-23, release date: 2014-06-18, Last modification date: 2023-09-20)
Primary citation	Span, I.,Wang, K.,Eisenreich, W.,Bacher, A.,Zhang, Y.,Oldfield, E.,Groll, M. Insights into the Binding of Pyridines to the Iron-Sulfur Enzyme IspH. J.Am.Chem.Soc., 136:7926-7932, 2014 Cited by PubMed: 24813236 DOI: 10.1021/ja501127j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation