4LVX

Structure of the THF riboswitch bound to tetrahydrobiopterin

Summary for 4LVX

Entry DOI	10.2210/pdb4lvx/pdb
Related	3SD3 4LVV 4LVW 4LVY 4LVZ 4LW0
Descriptor	THF riboswitch, 5,6,7,8-TETRAHYDROBIOPTERIN (3 entities in total)
Functional Keywords	aptamers, nucleotide, bacillus subtilis, bacterial proteins, base sequence, binding sites, calorimetry, folic acid, gene expression regulation, bacterial, guanine, leucovorin, ligands, magnesium, molecular sequence data, nucleic acid conformation, point mutation, protein binding, protein structure, secondary, rna, riboswitch, s-adenosylmethionine, streptococcus mutans, terminator regions, genetic, tetrahydrofolates, thermodynamics, transcription, three-way junction, pseudoknot, regulation, ncrna, tetrahydrobiopterin binding, mrna
Total number of polymer chains	1
Total formula weight	29331.64
Authors	Trausch, J.J.,Batey, R.T. (deposition date: 2013-07-26, release date: 2014-03-19, Last modification date: 2024-02-28)
Primary citation	Trausch, J.J.,Batey, R.T. A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21:205-216, 2014 Cited by PubMed: 24388757 DOI: 10.1016/j.chembiol.2013.11.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation