4KBZ
Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetylamino}-phenyl-acetic acid
Summary for 4KBZ
Entry DOI | 10.2210/pdb4kbz/pdb |
Related | 2G19 2G1M 2HBU |
Descriptor | Egl nine homolog 1, (2S)-({[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl}amino)(phenyl)ethanoic acid, FE (II) ION, ... (5 entities in total) |
Functional Keywords | jelly-roll beta-strand core, oxidoreductase, hif |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9GZT9 |
Total number of polymer chains | 1 |
Total formula weight | 27419.81 |
Authors | Kim, H.T.,Hong, Y.R.,Chang, H.J. (deposition date: 2013-04-24, release date: 2013-05-15, Last modification date: 2023-09-20) |
Primary citation | , |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report