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2HBU

Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor

Summary for 2HBU
Entry DOI10.2210/pdb2hbu/pdb
Related2HBT
DescriptorEgl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ... (4 entities in total)
Functional Keywordshif, prolyl hydroxylase, egln, 2-oxoglutarate, hypoxia inducible factor, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : Q9GZT9
Total number of polymer chains1
Total formula weight28169.18
Authors
Evdokimov, A.G.,Walter, R.L.,Mekel, M.,Pokross, M.E.,Kawamoto, R.,Boyer, A. (deposition date: 2006-06-14, release date: 2006-06-27, Last modification date: 2023-08-30)
Primary citationEvdokimov, A.G.,Walter, R.L.,Mekel, M.,Pokross, M.E.,Kawamoto, R.,Boyer, A.
Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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