4K8Y
Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1)
Summary for 4K8Y
Entry DOI | 10.2210/pdb4k8y/pdb |
Related | 1SFI 2bdg 2bdh 2bdi 4K1E 4KEL 4KGA |
Related PRD ID | PRD_001097 |
Descriptor | Kallikrein-4, Trypsin inhibitor 1 (3 entities in total) |
Functional Keywords | bowman-birk inhibitor, protease, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q9Y5K2 |
Total number of polymer chains | 2 |
Total formula weight | 25461.84 |
Authors | Ilyichova, O.V.,Swedberg, J.E.,de Veer, S.J.,Sit, K.C.,Harris, J.M.,Buckle, A.M. (deposition date: 2013-04-19, release date: 2014-04-23, Last modification date: 2023-11-08) |
Primary citation | Riley, B.T.,Ilyichova, O.,Costa, M.G.S.,Porebski, B.T.,de Veer, S.J.,Swedberg, J.E.,Kass, I.,Harris, J.M.,Hoke, D.E.,Buckle, A.M. Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics Sci Rep, 6:35385-35385, 2016 Cited by PubMed: 27767076DOI: 10.1038/srep35385 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
Download full validation report