4KGA

Crystal structure of kallikrein-related peptidase 4

Summary for 4KGA

Entry DOI	10.2210/pdb4kga/pdb
Related	2bdg 2bdh 2bdi 4K1E 4K8Y 4KEL
Descriptor	Kallikrein-4, NICKEL (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	klk4, kallikrein-4, serine protease, protease, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: Q9Y5K2
Total number of polymer chains	2
Total formula weight	48210.93
Authors	Ilyichova, O.V.,Swedberg, J.E.,de Veer, S.J.,Sit, K.C.,Harris, J.M.,Buckle, A.M. (deposition date: 2013-04-29, release date: 2014-04-30, Last modification date: 2023-11-08)
Primary citation	Riley, B.T.,Ilyichova, O.,Costa, M.G.S.,Porebski, B.T.,de Veer, S.J.,Swedberg, J.E.,Kass, I.,Harris, J.M.,Hoke, D.E.,Buckle, A.M. Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics Sci Rep, 6:35385-35385, 2016 Cited by PubMed: 27767076 DOI: 10.1038/srep35385 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation