4JA1

Structure of MMP3 complexed with a platinum-based inhibitor

Summary for 4JA1

• Entry DOI: 10.2210/pdb4ja1/pdb
• Related: 4DPE
• Descriptor: Stromelysin-1, ZINC ION, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: matrix metalloprotease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix (Probable): P08254
• Total number of polymer chains: 2
• Total formula weight: 40378.58

Authors

Belviso, B.D.,Arnesano, F.,Calderone, V.,Caliandro, R.,Natile, G.,Siliqi, D. (deposition date: 2013-02-18, release date: 2013-02-27, Last modification date: 2023-09-20)

• Primary citation: Belviso, B.D.,Caliandro, R.,Siliqi, D.,Calderone, V.,Arnesano, F.,Natile, G.; Structure of matrix metalloproteinase-3 with a platinum-based inhibitor.; Chem.Commun.(Camb.), 49:5492-5494, 2013; PubMed: 23660647; DOI: 10.1039/c3cc41278d

Experimental method

X-RAY DIFFRACTION (1.96 Å)