4J2X

CSL (RBP-Jk) with corepressor KyoT2 bound to DNA

Summary for 4J2X

• Entry DOI: 10.2210/pdb4j2x/pdb
• Related: 1TTU 2FO1 3BRD 3BRF 3BRG 3IAG
• Descriptor: Recombining binding protein suppressor of hairless, Four and a half LIM domains protein 1, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', ... (6 entities in total)
• Functional Keywords: lim domain containing protein, transcription factor corepressor, dna binding, nucleus, transcription-dna binding protein-dna complex, transcription/dna binding protein/dna
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: P31266; Isoform 1: Cytoplasm. Isoform 2: Nucleus: P97447
• Total number of polymer chains: 8
• Total formula weight: 120724.72

Authors

Collins, K.J.,Kovall, R.A. (deposition date: 2013-02-05, release date: 2013-11-06, Last modification date: 2023-09-20)

• Primary citation: Collins, K.J.,Yuan, Z.,Kovall, R.A.; Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling.; Structure, 22:70-81, 2014; PubMed: 24290140; DOI: 10.1016/j.str.2013.10.010

Experimental method

X-RAY DIFFRACTION (2.85 Å)