CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121

Summary for 3BRD

Related3BRF 3BRG
DescriptorLin-12 and glp-1 phenotype protein 1, isoform a, Protein lin-12/DNA Complex
Functional Keywordsprotein-dna complex, signaling, transcription, notch, dna-binding, ank repeat, developmental protein, differentiation, egf-like domain, glycoprotein, membrane, transmembrane, dna binding protein-dna complex, dna binding protein/dna
Biological sourceCaenorhabditis elegans
Cellular locationMembrane; Single-pass type I membrane protein P14585
Total number of polymer chains4
Total molecular weight67082.14
Wilson, J.J.,Kovall, R.A. (deposition date: 2007-12-21, release date: 2008-04-01, modification date: 2009-02-24)
Primary citation
Friedmann, D.R.,Wilson, J.J.,Kovall, R.A.
RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283:14781-14791, 2008
PubMed: 18381292
DOI: 10.1074/jbc.M709501200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27870.7%9.2%18.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3brd
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Molmil generated image of 3brd
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Molmil generated image of 3brd
rotated about y axis by 90°
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