4HP1

Crystal structure of Tet3 in complex with a non-CpG dsDNA

Summary for 4HP1

• Entry DOI: 10.2210/pdb4hp1/pdb
• Related: 4HP3
• Descriptor: DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION, ... (4 entities in total)
• Functional Keywords: cxxc, dna methylation, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Xenopus (Silurana) tropicalis (Western clawed frog)
• Total number of polymer chains: 3
• Total formula weight: 15917.68

Authors

Chao, X.,Tempel, W.,Bian, C.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2012-10-23, release date: 2012-12-05, Last modification date: 2024-04-03)

• Primary citation: Xu, Y.,Xu, C.,Kato, A.,Tempel, W.,Abreu, J.G.,Bian, C.,Hu, Y.,Hu, D.,Zhao, B.,Cerovina, T.,Diao, J.,Wu, F.,He, H.H.,Cui, Q.,Clark, E.,Ma, C.,Barbara, A.,Veenstra, G.J.,Xu, G.,Kaiser, U.B.,Liu, X.S.,Sugrue, S.P.,He, X.,Min, J.,Kato, Y.,Shi, Y.G.; Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.; Cell(Cambridge,Mass.), 151:1200-1213, 2012; PubMed: 23217707; DOI: 10.1016/j.cell.2012.11.014

Experimental method

X-RAY DIFFRACTION (2.25 Å)