4HP3

Crystal structure of Tet3 in complex with a CpG dsDNA

Summary for 4HP3

• Entry DOI: 10.2210/pdb4hp3/pdb
• Related: 4HP1
• Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ... (5 entities in total)
• Functional Keywords: cxxc, dna methylation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG)
• Total number of polymer chains: 3
• Total formula weight: 15887.65

Authors

Chao, X.,Tempel, W.,Bian, C.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2012-10-23, release date: 2012-12-05, Last modification date: 2024-04-03)

• Primary citation: Xu, Y.,Xu, C.,Kato, A.,Tempel, W.,Abreu, J.G.,Bian, C.,Hu, Y.,Hu, D.,Zhao, B.,Cerovina, T.,Diao, J.,Wu, F.,He, H.H.,Cui, Q.,Clark, E.,Ma, C.,Barbara, A.,Veenstra, G.J.,Xu, G.,Kaiser, U.B.,Liu, X.S.,Sugrue, S.P.,He, X.,Min, J.,Kato, Y.,Shi, Y.G.; Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.; Cell(Cambridge,Mass.), 151:1200-1213, 2012; PubMed: 23217707; DOI: 10.1016/j.cell.2012.11.014

Experimental method

X-RAY DIFFRACTION (2.05 Å)