4HLQ

Crystal structure of human rab1b bound to GDP and BEF3 in complex with the GAP domain of TBC1D20 from homo sapiens

Summary for 4HLQ

Entry DOI	10.2210/pdb4hlq/pdb
Related	4HL4
Descriptor	TBC1 domain family member 20, Ras-related protein Rab-1B, SULFATE ION, ... (7 entities in total)
Functional Keywords	rab1b, rabgap, fluorides, gtpase-activating proteins, rab gtp-binding proteins, hydrolase activator-protein transport complex, hydrolase activator/protein transport
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Multi-pass membrane protein (Potential): Q96BZ9 Membrane; Lipid-anchor; Cytoplasmic side: Q9H0U4
Total number of polymer chains	10
Total formula weight	276725.29
Authors	Gazdag, E.M.,Gavriljuk, K.,Itzen, A.,Koetting, C.,Gerwert, K.,Goody, R.S. (deposition date: 2012-10-17, release date: 2013-01-16, Last modification date: 2023-11-08)
Primary citation	Gavriljuk, K.,Gazdag, E.M.,Itzen, A.,Kotting, C.,Goody, R.S.,Gerwert, K. Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail. Proc.Natl.Acad.Sci.USA, 109:21348-21353, 2012 Cited by PubMed: 23236136 DOI: 10.1073/pnas.1214431110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation