4HL4

Crystal structure of the human TBC1D20 RabGAP domain

Summary for 4HL4

• Entry DOI: 10.2210/pdb4hl4/pdb
• Related: 4HLQ
• Descriptor: TBC1 domain family member 20, BERYLLIUM TRIFLUORIDE ION, ACETATE ION, ... (4 entities in total)
• Functional Keywords: tbc, rabgap, rab1b, hydrolase activator, catalytic domain, fluorides, gtpase-activating proteins, rab gtp-binding protein, gtp hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Multi-pass membrane protein (Potential): Q96BZ9
• Total number of polymer chains: 1
• Total formula weight: 33873.82

Authors

Gazdag, E.M.,Gavriljuk, K.,Itzen, A.,Koetting, C.,Gerwert, K.,Goody, R.S. (deposition date: 2012-10-16, release date: 2013-01-16, Last modification date: 2024-03-20)

• Primary citation: Gavriljuk, K.,Gazdag, E.M.,Itzen, A.,Kotting, C.,Goody, R.S.,Gerwert, K.; Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail.; Proc.Natl.Acad.Sci.USA, 109:21348-21353, 2012; PubMed: 23236136; DOI: 10.1073/pnas.1214431110

Experimental method

X-RAY DIFFRACTION (2.2 Å)