4H82

Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor.

Summary for 4H82

Entry DOI	10.2210/pdb4h82/pdb
Related	4H1Q 4H2E 4H30 4H3X 4H49 4H84
Descriptor	Matrix metalloproteinase-9, ZINC ION, CALCIUM ION, ... (9 entities in total)
Functional Keywords	hydrolase/twin inhibitor, zincin-like, gelatinase, collagenase (catalytic domain), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space, extracellular matrix : P14780
Total number of polymer chains	4
Total formula weight	75699.13
Authors	Antoni, C.,Stura, E.A.,Vera, L.,Cassar-Lajeunesse, E.,Nuti, E.,Dive, V.,Rossello, A. (deposition date: 2012-09-21, release date: 2013-05-01, Last modification date: 2023-09-20)
Primary citation	Antoni, C.,Vera, L.,Devel, L.,Catalani, M.P.,Czarny, B.,Cassar-Lajeunesse, E.,Nuti, E.,Rossello, A.,Dive, V.,Stura, E.A. Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182:246-254, 2013 Cited by PubMed: 23567804 DOI: 10.1016/j.jsb.2013.03.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation