4H5J
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P64 form)
Summary for 4H5J
| Entry DOI | 10.2210/pdb4h5j/pdb |
| Related | 4H5I |
| Descriptor | Guanine nucleotide-exchange factor SEC12, POTASSIUM ION (3 entities in total) |
| Functional Keywords | copii vesicle budding, potassium binding site, beta propeller, protein transport |
| Biological source | Saccharomyces cerevisiae (yeast) |
| Cellular location | Endoplasmic reticulum membrane; Single-pass type II membrane protein: P11655 |
| Total number of polymer chains | 2 |
| Total formula weight | 80693.75 |
| Authors | McMahon, C.,Jeffrey, P.D.,Hughson, F.M. (deposition date: 2012-09-18, release date: 2012-11-07, Last modification date: 2013-01-09) |
| Primary citation | McMahon, C.,Studer, S.M.,Clendinen, C.,Dann, G.P.,Jeffrey, P.D.,Hughson, F.M. The structure of sec12 implicates potassium ion coordination in sar1 activation. J.Biol.Chem., 287:43599-43606, 2012 Cited by PubMed: 23109340DOI: 10.1074/jbc.M112.420141 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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