4GO0
Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
Summary for 4GO0
Entry DOI | 10.2210/pdb4go0/pdb |
Related | 4GNZ 4GO2 |
Descriptor | Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (2 entities in total) |
Functional Keywords | aldehyde dehydrogenase, fdh, oxidoreductase |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Cytoplasm: P28037 |
Total number of polymer chains | 4 |
Total formula weight | 229403.62 |
Authors | Tsybovsky, Y. (deposition date: 2012-08-17, release date: 2013-01-23, Last modification date: 2023-09-13) |
Primary citation | Tsybovsky, Y.,Malakhau, Y.,Strickland, K.C.,Krupenko, S.A. The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1. Chem.Biol.Interact, 202:62-69, 2013 Cited by PubMed: 23295222DOI: 10.1016/j.cbi.2012.12.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.38 Å) |
Structure validation
Download full validation report