4GNZ

Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with NADP

Summary for 4GNZ

Entry DOI	10.2210/pdb4gnz/pdb
Related	4GO0 4GO2
Descriptor	Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	aldehyde dehydrogenase, fdh, oxidoreductase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cytoplasm: P28037
Total number of polymer chains	4
Total formula weight	232453.70
Authors	Tsybovsky, Y. (deposition date: 2012-08-17, release date: 2013-01-23, Last modification date: 2023-09-13)
Primary citation	Tsybovsky, Y.,Malakhau, Y.,Strickland, K.C.,Krupenko, S.A. The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1. Chem.Biol.Interact, 202:62-69, 2013 Cited by PubMed: 23295222 DOI: 10.1016/j.cbi.2012.12.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation