4GNU

Crystal structure of GES-5 carbapenemase

Summary for 4GNU

• Entry DOI: 10.2210/pdb4gnu/pdb
• Related: 4GOG 4H8R
• Descriptor: Beta-lactamase GES-5, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
• Functional Keywords: beta-lactamase, carbapenemase, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 62921.54

Authors

Smith, C.A.,Vakulenko, S.B. (deposition date: 2012-08-17, release date: 2013-07-24)

• Primary citation: Smith, C.A.,Frase, H.,Toth, M.,Kumarasiri, M.,Wiafe, K.,Munoz, J.,Mobashery, S.,Vakulenko, S.B.; Structural basis for progression toward the carbapenemase activity in the GES family of beta-lactamases.; J.Am.Chem.Soc., 134:19512-19515, 2012; PubMed: 23148776; DOI: 10.1021/ja308197j

Experimental method

X-RAY DIFFRACTION (1.09 Å)