4G8K

Intact sensor domain of human RNase L in the inactive signaling state

Summary for 4G8K

Entry DOI	10.2210/pdb4g8k/pdb
Related	4G8L
Descriptor	2-5A-dependent ribonuclease (2 entities in total)
Functional Keywords	ankyrin-repeat domain, single-stranded rna, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q05823
Total number of polymer chains	2
Total formula weight	74288.61
Authors	Han, Y.,Whitney, G.,Donovan, J.,Korennykh, A. (deposition date: 2012-07-23, release date: 2012-10-31, Last modification date: 2023-09-13)
Primary citation	Han, Y.,Whitney, G.,Donovan, J.,Korennykh, A. Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes. Cell Rep, 2:902-913, 2012 Cited by PubMed: 23084743 DOI: 10.1016/j.celrep.2012.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation