4F99
Human CDC7 kinase in complex with DBF4 and nucleotide
Summary for 4F99
Entry DOI | 10.2210/pdb4f99/pdb |
Related | 3PVG 4F99 4F9A 4F9B 4F9C |
Descriptor | Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | ser/thr protein kinase, transferase, phosphorylation, cell cycle, cell division, mitosis, s phase, serine/threonine-protein kinase, dbf4-dependent kinase, ddk, atp-binding, nucleotide-binding, zinc-binding, nucleus |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O00311 Q9UBU7 |
Total number of polymer chains | 2 |
Total formula weight | 58074.16 |
Authors | Hughes, S.,Cherepanov, P. (deposition date: 2012-05-18, release date: 2012-10-31, Last modification date: 2023-09-13) |
Primary citation | Hughes, S.,Elustondo, F.,Di Fonzo, A.,Leroux, F.G.,Wong, A.C.,Snijders, A.P.,Matthews, S.J.,Cherepanov, P. Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19:1101-1107, 2012 Cited by PubMed: 23064647DOI: 10.1038/nsmb.2404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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