4F99
Human CDC7 kinase in complex with DBF4 and nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cell division cycle 7-related protein kinase | polymer | 361 | 40633.8 | 1 | UniProt (O00311) Pfam (PF00069) In PDB | Homo sapiens (human) | CDC7-related kinase, HsCdc7, huCdc7 |
| 2 | B | Protein DBF4 homolog A | polymer | 144 | 16923.4 | 1 | UniProt (Q9UBU7) Pfam (PF07535) In PDB | Homo sapiens (human) | Activator of S phase kinase, Chiffon homolog A, DBF4-type zinc finger-containing protein 1 |
| 3 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 37 - 359 (UniProt: O00311)
A: 360 - 529 (UniProt: O00311)
A: 530 - 574 (UniProt: O00311)
B: 210 - 350 (UniProt: Q9UBU7)
| PDB | External Database | Details |
|---|---|---|
| Met 36 | - | expression tag |
A: 530 - 574 (UniProt: O00311)
B: 210 - 350 (UniProt: Q9UBU7)
| PDB | External Database | Details |
|---|---|---|
| Gly 207 | - | expression tag |
| Pro 208 | - | expression tag |
| Gly 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57557.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 516.9 | |
| All* | Total formula weight | 58074.2 |
