4F59
Triple mutant Src SH2 domain
Summary for 4F59
Entry DOI | 10.2210/pdb4f59/pdb |
Related | 4F5A 4F5B |
Descriptor | Proto-oncogene tyrosine-protein kinase Src (2 entities in total) |
Functional Keywords | sh2 domain, cell signalling, phosphotyrosine binding, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane: P12931 |
Total number of polymer chains | 1 |
Total formula weight | 12699.32 |
Authors | Kaneko, T.,Huang, H.,Cao, X.,Li, C.,Voss, C.,Sidhu, S.S.,Li, S.S. (deposition date: 2012-05-12, release date: 2012-10-03, Last modification date: 2024-02-28) |
Primary citation | Kaneko, T.,Huang, H.,Cao, X.,Li, X.,Li, C.,Voss, C.,Sidhu, S.S.,Li, S.S. Superbinder SH2 Domains Act as Antagonists of Cell Signaling. Sci.Signal., 5:ra68-ra68, 2012 Cited by PubMed: 23012655DOI: 10.1126/scisignal.2003021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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