4EBN

BlaC Amoxicillin Acyl-Intermediate Complex

Summary for 4EBN

• Entry DOI: 10.2210/pdb4ebn/pdb
• Related: 3VFF 3VFH 4EBI 4EBL 4EBM 4EBO 4EBP
• Descriptor: Beta-lactamase, PHOSPHATE ION, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
• Functional Keywords: ambler class a beta-lactamase, beta-lactamase, serine hydrolase, esterase, hydrolase-antibiotic complex, structural genomics, tb structural genomics consortium, tbsgc, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane; Lipid-anchor (Potential): P0C5C1
• Total number of polymer chains: 4
• Total formula weight: 114163.42

Authors

Mire, J.A.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2012-03-23, release date: 2013-04-03, Last modification date: 2023-09-13)

• Primary citation: Mire, J.A.,Pai, P.,Siddiqi, N.,Russell, D.H.,Rubin, E.J.,Sacchettini, J.C.; Faropenem is Effective Against Mycobacterium tuberculosis in vitro and in vivo; To be Published,

Experimental method

X-RAY DIFFRACTION (2.85 Å)