4E82
Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)
Summary for 4E82
Entry DOI | 10.2210/pdb4e82/pdb |
Related | 1ZMP 4E83 4E86 |
Descriptor | Defensin-5 (2 entities in total) |
Functional Keywords | monomeric variant, antimicrobial peptide, glu21 methylation, paneth cells, antimicrobial protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: Q01523 |
Total number of polymer chains | 2 |
Total formula weight | 7216.51 |
Authors | Pazgier, M. (deposition date: 2012-03-19, release date: 2012-05-16, Last modification date: 2023-11-15) |
Primary citation | Rajabi, M.,Ericksen, B.,Wu, X.,de Leeuw, E.,Zhao, L.,Pazgier, M.,Lu, W. Functional determinants of human enteric {alpha}-defensin HD5: crucial role for hydrophobicity at dimer interface. J.Biol.Chem., 287:21615-21627, 2012 Cited by PubMed: 22573326DOI: 10.1074/jbc.M112.367995 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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